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美國 Fluorochorome 公司于1985 年成立于美國科羅拉多州丹佛市，Fluorochorome 一直致力于熒光染料的研究與開發，其專利產品Fluoro-Gold（熒光金）自 1985 年來在全球范圍內被廣泛應用，并有大量的參考文獻。同時，Fluorochrome公司特別開發了高靈敏度的 Antibody to Fluoro-Gold 、以及Fluoro-Ruby（紅色熒光金）等產品，Fluorochrome 公司堅 持以優質的產品和熱情的服務贏得了良好的知名度和口碑。
Notice: The original and only true Fluoro-Gold (Fluorogold) is produced by Fluorochrome, LLC and marketed by Fluorochrome, LLC and Histo-Chem Inc.Fluoro-Gold (Fluorogold) is an exclusive product of Fluorochrome, LLC. It has been sold by Fluorochrome and widely used since 1985. Other companies are marketing a product they claim is the same as or equivalent to Fluoro-Gold. In fact, the chemical structures of these compounds seem to be different from Fluoro-Gold. Certain physical properties of the compounds may be very different.
Tosolini A.P., Mohan R, Morris R., “Targeting the full length of the motor end plates regions in the mouse forelimb increases the uptake of Fluoro-Gold into corresponding spinal cord motor neurons,” Frontiers in Neurology (2013) 1-10.
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Bowyer, J.F. and Schmued, L., Fluoro-Ruby labeling prior to an amphetamine neurotoxic insult shows a definitive massive loss of dopaminergic terminals and axons in caudateputamen. Brain Res., 1075, (2006) 236-239.
*Schmued, L.C., “Anti-retrograde and retrograde neuroanatomical tract tracing with fluorescent compounds,” Neuroscience Protocols, 94-050-02 (1994) 1-15.
Van Bockstaele, E.J., Wright, A.M., Cestari, D.M., and Pickel, V.M., “Immunolabeling of retrogradely transported Fluoro-Gold: sensitivity and application to ultrastructural analysis of transmitter-specific mesolimbic circuitry,” Journal of Neuroscience Methods, 55 (1994) 65-78.
*Bowyer, J.F., Gough, B., Broening, H.W., Newport, G.D., and Schmued, L., “Fluoro-Gold and Pentamidine Inhibit the In Vitro and In Vivo Release of Dopamine in the Striatum of Rat,” The Journal of Pharmacology and Experimental Therapeutics, 266 (1993) 1066-1074.
Balercia, G., Chen, S., and Bentivoglio, M., “Electron microscopic analysis of fluorescent neuronal labeling after photoconversion,” Journal of Neuroscience Methods 45 (1992) 87-98. [Link]
*Chang, H.T., Kuo, H., Whittaker, J.A., and Cooper, N.G.F., “Light and electron microscopic analysis of projection neurons retrogradely labeled with Fluoro-Gold notes on the application of antibodies of Fluoro-Gold,” Journal of Neuroscience Methods, 35 (1990) 31-37.
Schmued, L., “Fluoro-Gold and 4-Acetamido-4′-isothiocyanostilbene-2,2’disulfonic Acid: Use of Substituted Stilbenes in Neuroanatomical Studies,” Methods in Neurosciences, 3 (1990) 317-330.
Schmued, L., Kyriakidis, K., & Heimer, L., In vivo anterograde and retrograde axonal transport of the fluorescent rhodamine-dextran-amine, Fluoro-Ruby, within the CNS. Brain Res, 526 (1990) 127-134.
Schmued, L.C., Kyriakidis, K., Fallon, J.H., and Ribak, C.E., “Neurons containing retrogradely transported Fluoro-Gold exhibit a variety of iysosomal profiles: a combined brightfield, fluorescence and electron microscopic study,” Journal of Neurocytology, 18 (1989) 333-343.
*Pieribone, V.A., Aston-Jones, G., “The iontophoretic application of Flouro-Gold for the study of the afferents to deep brain nuclei,” Brain Research 475 (1988) 259-271. [Link]
Reep, R.L., Baccala, M.J., Booth, M.P., and Goodwin, G.S., “Combined retrograde and anterograde tracing of neuronal connections: Fluoro-Gold and autoradiography,” Journal of Neuroscience Methods, 23 (1988) 1-5.
*Schmued, L.C. and Fallon, J.H., “Fluoro-Gold: a fluorescent retrograde axonal tracer with numerous unique properties,” Brain Research, 377 (1986) 147-154.